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Article

Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCN1A: implications for linkage-disequilibrium gene mapping.

American journal of human genetics - 1 Sept 2003

Weale Mike E, Depondt Chantal, Macdonald Stuart J, Smith Alice, Lai Poh San, Shorvon Simon D, Wood Nicholas W, Goldstein David B

Abstract excerpt

Association studies are widely seen as the most promising approach for finding polymorphisms that influence genetically complex traits, such as common diseases and responses to their treatment. Considerable interest has therefore recently focused on the development of methods that efficiently screen genomic regions or whole genomes for gene variants associated with complex phenotypes. One key element in this...

Topics

Adult
Asian People
Child
Epilepsy
Female
Genetic Techniques
Haplotypes
Humans
Linkage Disequilibrium
Male
NAV1.1 Voltage-Gated Sodium Channel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nerve Tissue Proteins

Polymorphism, Single Nucleotide

Singapore

Sodium Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 12900796
DOI: 10.1086/378098
PMCID: PMC1180680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12900796-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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