Article
The effect of SNP marker density on the efficacy of haplotype tagging SNPs--a warning.
Annals of human genetics - 1 Mar 2005
Iles Mark M
Abstract excerpt
We investigate here the efficacy of selecting haplotype tagging SNPs at different marker densities (2kb-10kb). Our results are based on publicly available data on 5324 markers with a median spacing of 1kb from chromosome 20. We find that whatever density of SNPs is used, htSNP analysis indicates in most cases that at least 80% of the variation can be captured using a subset of SNPs. However, as marker density...
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