The effect of SNP marker density on the efficacy of haplotype tagging SNPs--a warning.

doi:10.1046/j.1529-8817.2004.00141.x

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Article

The effect of SNP marker density on the efficacy of haplotype tagging SNPs--a warning.

Annals of human genetics - 1 Mar 2005

Iles Mark M

Abstract excerpt

We investigate here the efficacy of selecting haplotype tagging SNPs at different marker densities (2kb-10kb). Our results are based on publicly available data on 5324 markers with a median spacing of 1kb from chromosome 20. We find that whatever density of SNPs is used, htSNP analysis indicates...

Topics

Chromosomes, Human, Pair 20
Haplotypes
Humans
Polymorphism, Single Nucleotide

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