Article
Accounting for genotyping errors in tagging SNP selection.
Annals of human genetics - 1 Jul 2007
Liu W, Yang T, Zhao W, Chase G A
Abstract excerpt
One limitation of the existing tagging SNP selection algorithms is that they assume the reported genotypes are error free. However, genotyping errors are often unavoidable in practice. Many tagging SNP selection methods depend heavily on the estimated haplotype frequencies. Recent studies have demonstrated that even slight genotyping errors can lead to serious consequences with regard to haplotype reconstruction...
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