Article
Approximation properties of haplotype tagging.
BMC bioinformatics - 9 Jan 2006
Vinterbo Staal A, Dreiseitl Stephan, Ohno-Machado Lucila
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns, disease association studies are facilitated by identifying SNPs that allow the unique identification of such patterns. This process, known as haplotype tagging, is formulated as a combinatorial optimization problem and analyzed in terms...
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