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Article

CXCR5/CXCL13 interaction is important for double-negative regulatory T cell homing to cardiac allografts.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2006

Lee Boris P-L, Chen Wenhao, Shi Hui, Der Sandy D, Förster Reinhold, Zhang Li

Abstract excerpt

Accumulating evidence indicates that regulatory T (Treg) cells control development of various diseases both systemically and locally. However, molecular mechanisms involved in Treg cell homing remain elusive. We have shown previously that alphabetaTCR(+)CD3(+)CD4(-)CD8(-) double-negative (DN) Treg cells selectively accumulate in tolerant allografts to maintain localized immune regulation. However, the molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16621993
DOI: 10.4049/jimmunol.176.9.5276

Genes

CXCR5
CXCL13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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