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Article

Chemoattractant Signals and Adhesion Molecules Promoting Human Regulatory T Cell Recruitment to Porcine Endothelium.

Transplantation - 1 Apr 2016

Ehirchiou Driss, Muller Yannick D, Chicheportiche Rachel, Heyrani Nobari Ruhollah, Madelon Natacha, Schneider Mårten K J, Seebach Jörg D

Abstract excerpt

BACKGROUND: Human CD4+CD25+Foxp3+ T regulatory cells (huTreg) suppress CD4+ T cell-mediated antipig xenogeneic responses in vitro and might therefore be used to induce xenograft tolerance. The present study investigated the role of the adhesion molecules, their porcine ligands, and the chemoattractant factors that may promote the recruitment of huTreg to porcine aortic endothelial cells (PAEC) and their capacity...

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Source

Identifiers

PMID: 26720299
DOI: 10.1097/TP.0000000000001034

Genes

CCL17
CCR4
CXCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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