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Article

Peripherally circulating CD4⁺ FOXP3⁺ CXCR3⁺ T regulatory cells correlate with renal allograft function.

Scandinavian journal of immunology - 1 Sept 2012

Hoerning A, Köhler S, Jun C, Tebbe B, Fu J, Menke J, Wilde B, Dolff S, Feldkamp T, Briscoe D M, Kribben A, Hoyer P F, Witzke O

Abstract excerpt

Peripheral immunoregulation depends on T regulatory cell trafficking into the allograft to modulate the local alloresponse. Little is known about the relevance of trafficking receptors for Tregs after solid organ transplantation in humans. In this study, expression of the peripheral chemokine receptors CXCR3 and CCR5 on CD4⁺ FOXP3⁺ Treg cells was analysed and correlated with allograft function in renal transplant...

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Topics

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Share to CD4 Antigens
Share to Chemotaxis, Leukocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerular Filtration Rate

Share to Graft Rejection

Share to Receptors, CXCR3

Share to T-Lymphocyte Subsets

Share to T-Lymphocytes, Regulatory

Share to Transplantation, Homologous

Source

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Identifiers

PMID: 22670785
DOI: 10.1111/j.1365-3083.2012.02732.x
PMCID: PMC3425730

Genes

CXCR3
FOXP3
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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