Article
An RNA sensor for intracellular Mg(2+).
Cell - 7 Apr 2006
Cromie Michael J, Shi Yixin, Latifi Tammy, Groisman Eduardo A
Abstract excerpt
Most RNA molecules require Mg(2+) for their structure and enzymatic properties. Here we report the first example of an RNA serving as sensor for cytoplasmic Mg(2+). We establish that expression of the Mg(2+) transporter MgtA of Salmonella enterica serovar Typhimurium is controlled by its 5' untranslated region (5'UTR). We show that the 5'UTR of the mgtA gene can adopt different stem-loop structures depending on...
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