Article
Recombination resulting in unusual features in the polyomavirus genome isolated from a murine tumor cell line.
Journal of virology - 1 Aug 1990
Streuli C H, Krauzewicz N S, Griffin B E
Abstract excerpt
Polyomavirus-induced tumor formation in the adult natural mouse host has been investigated. Tumors were produced in nude mice with the transformation-defective mutant strain NG18 after a long latency period by apparent activation of a cryptic endogenous transforming viral function. A tumor cell line, designated ScB, was established and characterized. Cells from this morphologically distinct line were unusual in...
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