Article
Recombination resulting in unusual features in the polyomavirus genome isolated from a murine tumor cell line.
Journal of virology - 1 Aug 1990
Streuli C H, Krauzewicz N S, Griffin B E
Abstract excerpt
Polyomavirus-induced tumor formation in the adult natural mouse host has been investigated. Tumors were produced in nude mice with the transformation-defective mutant strain NG18 after a long latency period by apparent activation of a cryptic endogenous transforming viral function. A tumor cell l...
Topics
- Animals
- Base Sequence
- Blotting, Northern
- Blotting, Southern
- Cell Transformation, Viral
- Cells, Cultured
- Chromosome Inversion
- Cloning, Molecular
- DNA, Viral
- Female
- Gene Library
- Genes, Viral
