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Article

The role of calmodulin recruitment in Ca2+ stimulation of adenylyl cyclase type 8.

The Journal of biological chemistry - 23 Jun 2006

Simpson Rachel E, Ciruela Antonio, Cooper Dermot M F

Abstract excerpt

Ca2+ stimulation of adenylyl cyclase type 8 (AC8) is mediated by calmodulin (CaM). An earlier study identified two CaM binding sites in AC8; one that was apparently not essential for AC8 activity, located at the N terminus, and a second site that was critical for Ca2+ stimulation, found at the C terminus (Gu, C., and Cooper, D. M. F. (1999) J. Biol. Chem. 274, 8012-8021). This study explores the role of these two...

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PMID: 16613843
DOI: 10.1074/jbc.M510992200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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