Article
Severity of cardiovascular disease in postmenopausal women: associations with common estrogen receptor alpha polymorphic variants.
European journal of endocrinology - 1 Apr 2007
Alevizaki M, Saltiki K, Cimponeriu A, Kanakakis I, Xita N, Alevizaki C C, Georgiou I, Sarika H-L
Abstract excerpt
OBJECTIVE: Impaired estrogen action is a risk factor for coronary artery disease (CAD). Associations of CAD with estrogen receptor alpha (ER alpha) polymorphisms, which may influence sensitivity to estrogen, have been reported for men; the data concerning women are not conclusive. We investigated the association of common ER alpha polymorphisms with the severity of CAD and with metabolic and reproductive factors...
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