Article
Estrogen receptor α gene PvuII polymorphism and coronary artery disease: a meta-analysis of 21 studies.
Journal of Zhejiang University. Science. B - 1 Mar 2014
Ding Jie, Xu Hui, Yin Xiang, Zhang Fu-rong, Pan Xiao-ping, Gu Yi-an, Chen Jun-zhu, Guo Xiao-gang
Abstract excerpt
The association between the estrogen receptor α gene (ESR1) PvuII polymorphism (c.454-397T>C) and coronary artery disease (CAD) is controversial. Thus, we conducted a meta-analysis to evaluate the relationship. Data were collected from 21 studies encompassing 9926 CAD patients and 16710 controls. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the relationship between PvuII polymorphism...
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