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Article

Fitness constraints on immune escape from HIV: Implications of envelope as a target for both HIV-specific T cells and antibody.

Current HIV research - 1 Apr 2006

Peut Viv, Kent Stephen J

Abstract excerpt

Sterilising immunity against HIV-1 infection, whilst ideal, appears an unrealistic vaccination goal in the short term. More achievable is slowing the progression to disease and decreasing transmission by mounting strong T cell and neutralising antibody responses to maintain low viral loads. However, in both acute and chronic infection, mutant virus is selected to escape both arms of the adaptive immune system....

Read the complete abstract on PubMed

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Share to Antibodies, Viral
Share to HIV-1
Share to HIV Envelope Protein gp120

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Mutation

Share to T-Lymphocytes, Cytotoxic

Share to Viral Load

Share to Virus Replication

Source

Identifiers

PMID: 16611057
DOI: 10.2174/157016206776055110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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