Article
Molecular classification of fatty liver by high-throughput profiling of protein post-translational modifications.
The Journal of pathology - 1 Apr 2016
Urasaki Yasuyo, Fiscus Ronald R, Le Thuc T
Abstract excerpt
We describe an alternative approach to classifying fatty liver by profiling protein post-translational modifications (PTMs) with high-throughput capillary isoelectric focusing (cIEF) immunoassays. Four strains of mice were studied, with fatty livers induced by different causes, such as ageing, genetic mutation, acute drug usage, and high-fat diet. Nutrient-sensitive PTMs of a panel of 12 liver metabolic and...
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