Article
The role of an upstream promoter interaction in initiation of bacterial transcription.
The EMBO journal - 19 Apr 2006
Nechaev Sergei, Geiduschek E Peter
Abstract excerpt
The bacterial RNA polymerase (RNAP) recognizes promoters through sequence-specific contacts of its promoter-specificity components (sigma) with two DNA sequence motifs. Contacts with the upstream ('-35') promoter motif are made by sigma domain 4 attached to the flap domain of the RNAP beta subunit. Bacteriophage T4 late promoters consist solely of an extended downstream ('-10') motif specifically recognized by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
