Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The bacteriophage T4 late-transcription coactivator gp33 binds the flap domain of Escherichia coli RNA polymerase.

Proceedings of the National Academy of Sciences of the United States of America - 14 Dec 2004

Nechaev Sergei, Kamali-Moghaddam Masood, André Estelle, Léonetti Jean-Paul, Geiduschek E Peter

Abstract excerpt

Transcription of bacteriophage T4 late genes requires concomitant DNA replication. T4 late promoters, which consist of a single 8-bp -10 motif, are recognized by a holoenzyme containing Escherichia coli RNA polymerase core and the T4-encoded promoter specificity subunit, gp55. Initiation of transcription at these promoters by gp55-holoenzyme is inefficient, but is greatly activated by the DNA-loaded DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophage T4
Share to Binding, Competitive

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Directed RNA Polymerases

Share to Gene Expression Regulation, Viral

Share to Protein Structure, Tertiary

Share to Sequence Alignment

Share to Transcription, Genetic

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 15574501
DOI: 10.1073/pnas.0408028101
PMCID: PMC535105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The bacteriophage T4 late-transcription coactivator gp33 binds the flap domain of Escherichia coli RNA polymerase.PMID 15574501Read ↗

The role of an upstream promoter interaction in initiation of bacterial transcription.Semantic proximity Read ↗

Mutational and functional analysis of a segment of the sigma family bacteriophage T4 late promoter recognition protein gp55.Semantic proximity Read ↗

Multiple roles of the RNA polymerase beta subunit flap domain in sigma 54-dependent transcription.Semantic proximity Read ↗

Mutational analysis of sigma70 region 4 needed for appropriation by the bacteriophage T4 transcription factors AsiA and MotA.Semantic proximity Read ↗

On the role of the Escherichia coli RNA polymerase sigma 70 region 4.2 and alpha-subunit C-terminal domains in promoter complex formation on the extended -10 galP1 promoter.Semantic proximity Read ↗

A mutation within the β subunit of Escherichia coli RNA polymerase impairs transcription from bacteriophage T4 middle promoters.Semantic proximity Read ↗

The role of the bacterial RNA polymerase beta subunit flexible flap domain in transcription termination.Semantic proximity Read ↗

Identification of upstream sequences essential for activation of a bacteriophage P2 late promoter.Semantic proximity Read ↗

Mutational analysis of the activator of late transcription, Alt, in the lactococcal bacteriophage TP901-1.Semantic proximity Read ↗

A mutation in region 1.1 of sigma70 affects promoter DNA binding by Escherichia coli RNA polymerase holoenzyme.Semantic proximity Read ↗

Interplay between σ region 3.2 and secondary channel factors during promoter escape by bacterial RNA polymerase.Semantic proximity Read ↗

A Mutation in the C-terminal domain of the RNA polymerase alpha subunit that destabilizes the open complexes formed at the phage phi 29 late A3 promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.