Article
Differential role of base pairs on gal promoters strength.
Journal of molecular biology - 27 Feb 2015
Lewis Dale E A, Le Phuoc, Adhya Sankar
Abstract excerpt
Sequence alignments of promoters in prokaryotes postulated that the frequency of occurrence of a base pair at a given position of promoter elements reflects its contribution to intrinsic promoter strength. We directly assessed the contribution of the four base pairs in each position in the intrinsic promoter strength by keeping the context constant in Escherichia coli cAMP-CRP (cAMP receptor protein) regulated...
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