Article
Genetic analyses of non-small cell lung cancer in Jewish Israeli patients.
The Israel Medical Association journal : IMAJ - 1 Mar 2006
Schayek Hagit, Krupsky Meir, Yaron Penina, Yellin Alon, Simansky David A, Friedman Eitan
Abstract excerpt
BACKGROUND: The contribution of the abnormal DNA mismatch repair system to non-small cell lung cancer tumorigenesis is controversial and has not been reported in Jewish Israeli patients. Similarly, the involvement of 3p deletions in NSCLC in the same population has not been assessed. OBJECTIVES: To assess the contribution of the DNA-MMR system to NSCLC pathogenesis by analyzing microsatellite instability, and...
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