Article
Telomeric silencing of an open reading frame in Saccharomyces cerevisiae.
Genetics - 1 Jun 2006
Barton Arnold B, Kaback David B
Abstract excerpt
The endmost chromosome I ORF is silenced by a natural telomere position effect. YAR073W/IMD1 was found to be transcribed at much higher levels in sir3 mutants and when its adjacent telomere was removed from it. These results suggest that telomeres play a role in silencing actual genes.
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