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Article

[The telomere position effect: silence in the back row!].

Medecine sciences : M/S - 1 Feb 2014

Decottignies Anabelle

Abstract excerpt

Heterochromatin displays repressive histone marks that down-regulate transcription. In the absence of specialized barriers, these repressive marks spread onto nearby nucleosomes and induce transcriptional silencing of these regions. Accordingly, in various species, transgenes that are experimentally inserted directly next to telomeric repeats are silenced. Transcriptional repression induced by the spreading of...

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Identifiers

PMID: 24572116
DOI: 10.1051/medsci/20143002015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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