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Article

Differential association of Orc1 and Sir2 proteins to telomeric domains in <i>Plasmodium falciparum</i>

4 Jun 2008

Abstract excerpt

Telomeres have the capacity to recruit proteins that facilitate the spreading of heterochromatin into subtelomeric DNA regions. In the human protozoan pathogen Plasmodium falciparum, the telomere-associated protein Sir2 has been shown to control the silencing of members of virulence genes at some, but not all, chromosome-end loci, indicating that additional proteins are involved in telomere position effect. Here,...

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PMID: 18525026
DOI: 10.1242/jcs.026427

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