Article
Altered vulnerability to asthma at various levels of ambient Benzo[a]Pyrene by CTLA4, STAT4 and CYP2E1 polymorphisms.
Environmental pollution (Barking, Essex : 1987) - 1 Dec 2017
Choi Hyunok, Tabashidze Nana, Rossner Pavel, Dostal Miroslav, Pastorkova Anna, Kong Sek Won, Gmuender Hans, Sram Radim J
Abstract excerpt
BACKGROUND: Within fossil- and solid-fuel dependent geographic locations, mechanisms of air pollution-induced asthma remains unknown. In particular, sources of greater genetic susceptibility to airborne carcinogen, namely, benzo[a]pyrene (B[a]P) has never been investigated beyond that of a few well known genes. OBJECTIVES: To deepen our understanding on how the genotypic variations within the candidate genes...
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