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Article

Interactive effects between CYP1A1 genotypes and environmental polychlorinated dibenzo-p-dioxins and dibenzofurans exposures on liver function profile.

Journal of toxicology and environmental health. Part A - 1 Feb 2006

Chen Hsiu-Ling, Su Huey-Jen, Wang Ying-Jan, Guo Yue-Liang, Liao Pao-Chi, Lee Ching-Chang

Abstract excerpt

Previous studies reported that polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) induced hepatic cytochrome P-4501A1 (CYP1A1). The aim of this study was to examine the interactive influence of CYP1A1 genotypes and PCDD/Fs exposure on liver function profile. PCDD/Fs levels and liver function parameters were determined in serum and correlated with genetic polymorphism of CYP1A1/Msp 1 in 225 human...

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PMID: 16407087
DOI: 10.1080/15287390500227456

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GPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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