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Prenatal perfluorooctanoic acid exposure and glutathione s-transferase T1/M1 genotypes and their association with atopic dermatitis at 2 years of age

16 Jan 2019

Abstract excerpt

BACKGROUND: Perfluoroalkyl substance (PFAS) exposure was found associated with atopic diseases. Atopic dermatitis (AD) is a childhood skin disorder. However, the effect of interaction between PFASs and glutathione S-transferase (GST) T1/M1 genotype on AD remains unclear. OBJECTIVE: To investigate the association between gene-environmental interaction and childhood AD using a birth cohort study. METHODS: From 2001...

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PMID: 30650146
DOI: 10.1371/journal.pone.0210708

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