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Article

Genetic variants affecting chemical mediated skin immunotoxicity.

Journal of toxicology and environmental health. Part B, Critical reviews - 17 Feb 2022

Rodrigues de Souza Isisdoris, Savio de Araujo-Souza Patrícia, Morais Leme Daniela

Abstract excerpt

The skin is an immune-competent organ and this function may be impaired by exposure to chemicals, which may ultimately result in immune-mediated dermal disorders. Interindividual variability to chemical-induced skin immune reactions is associated with intrinsic individual characteristics and their genomes. In the last 30-40 years, several genes influencing susceptibility to skin immune reactions were identified....

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PMID: 34979876
DOI: 10.1080/10937404.2021.2013372

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