Article
Susceptibility and exposure biomarkers in people exposed to PAHs from diesel exhaust.
Toxicology letters - 15 Sept 2003
Adonis M, Martínez V, Riquelme R, Ancic P, González G, Tapia R, Castro M, Lucas D, Berthou F, Gil L
Abstract excerpt
Xenobiotic metabolizing enzymes, especially CYP1A1 and GSTM1, are involved in the activation and conjugation of PAHs and are controlled by polymorphic genes. PAHs released from diesel emissions in many cities of the world, especially in developing countries, contribute significantly to the toxic effects of airborne inhalable particles. We have evaluated the gene-environment interaction in Santiago of Chile,...
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