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Article

Target genes of the WNT/beta-catenin pathway in Wilms tumors.

Genes, chromosomes & cancer - 1 Jun 2006

Zirn Birgit, Samans Birgit, Wittmann Stefanie, Pietsch Thorsten, Leuschner Ivo, Graf Norbert, Gessler Manfred

Abstract excerpt

The WNT/beta-catenin pathway is involved in numerous human cancers. Mutations of the CTNNB1 (beta-catenin) gene have also been detected in a subset of pediatric Wilms tumors, but the target genes of the deregulated WNT/beta-catenin pathway in these tumors have yet to be identified. To compare gene expression profiles of Wilms tumors with and without mutations of CTNNB1, we used 11.5-k cDNA microarrays. Most of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 16575872
DOI: 10.1002/gcc.20319

Genes

CTNNB1
APCDD1
EDN3
EDNRA
ENPP2
PITX2
WIF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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