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Article

Role of the Wilms’ tumor 1 gene in the aberrant biological behavior of leukemic cells and the related mechanisms

6 Oct 2014

Abstract excerpt

The Wilms' tumor 1 (WT1) gene is one of the regulating factors in cell proliferation and development. It is a double-functional gene: an oncogene and a tumor suppressor. This gene was found to be highly expressed in many leukemic cell lines and in patients with acute myeloid leukemia. In the present study, we demonstrated that the WT1 gene was commonly expressed in leukemic cell lines apart from U937 cells. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25310451
DOI: 10.3892/or.2014.3529

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