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Article

Genomic imprinting in Dicer1-hypomorphic mice.

Cytogenetic and genome research - 1 Jan 2006

Fukasawa M, Morita S, Kimura M, Horii T, Ochiya T, Hatada I

Abstract excerpt

To address the function of RNA interference (RNAi) in transcriptional silencing in mammals, we analyzed genomic imprinting in Dicer1-hypomorphic mice, in which Dicer1 expression was significantly reduced. We did not observe any abnormality in the allelic expression of imprinted genes in these mice or their offspring, suggesting that reduced expression of Dicer1 did not significantly affect the maintenance and...

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PMID: 16575173
DOI: 10.1159/000090825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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