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Article

Association analysis of common variants of ELN, NOS2A, APOE and ACE2 to intracranial aneurysm.

Stroke - 1 May 2006

Mineharu Youhei, Inoue Kayoko, Inoue Sumiko, Yamada Shigeki, Nozaki Kazuhiko, Takenaka Katsunobu, Hashimoto Nobuo, Koizumi Akio

Abstract excerpt

BACKGROUND AND PURPOSE: Previous studies have shown positive evidence of linkage of the intracranial aneurysm (IA) at chromosome 7q11, 17cen, 19q13, and Xp22. These regions contain elastin (ELN), nitric oxide synthetase 2A (NOS2A), apolipoprotein E (APOE), and angiotensin-I converting enzyme 2 (ACE2), which are considered to be promising candidate genes for IA. We aimed to examine the association of...

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Source

Identifiers

PMID: 16574921
DOI: 10.1161/01.STR.0000217408.91389.4d

Genes

ACE2
APOE
ELN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Association analysis of common variants of ELN, NOS2A, APOE and ACE2 to intracranial aneurysm.PMID 16574921Read ↗

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Genetic Risk Assessment of Elastin Gene Polymorphisms with Intracranial Aneurysm in Koreans.Semantic proximity Read ↗

Extended single nucleotide polymorphism and haplotype analysis of the elastin gene in Caucasians with intracranial aneurysms provides evidence for racially/ethnically based differences.Semantic proximity Read ↗

Subarachnoid hemorrhage: tests of association with apolipoprotein E and elastin genes.Semantic proximity Read ↗

A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.Semantic proximity Read ↗

Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk.Semantic proximity Read ↗

Elastin polymorphism haplotype and intracranial aneurysms are not associated in Central Europe.Semantic proximity Read ↗

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