Article
Extended single nucleotide polymorphism and haplotype analysis of the elastin gene in Caucasians with intracranial aneurysms provides evidence for racially/ethnically based differences.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2004
Krex Dietmar, König Inke R, Ziegler Andreas, Schackert Hans K, Schackert Gabriele
Abstract excerpt
BACKGROUND: There is growing evidence that genetic variants have an impact on the pathogenesis of intracranial aneurysm (IA). Recently, the genetic locus around the elastin gene (7q11) has been identified as linked to IA in a Japanese population. Our aim was to confirm these results in Caucasian populations. METHODS: We conducted a case-control study in 120 Caucasian patients with IA and 172 controls to...
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