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Article

Confirmation of chromosome 7q11 locus for predisposition to intracranial aneurysm.

Human genetics - 1 Feb 2004

Farnham James M, Camp Nicola J, Neuhausen Susan L, Tsuruda Jay, Parker Dennis, MacDonald Joel, Cannon-Albright Lisa A

Abstract excerpt

A significant linkage of intracranial aneurysm (IA) has recently been reported to chromosomal region 7q11 (MLS=3.22) in a genomic search of 85 Japanese nuclear families with at least two affected siblings (104 sib pairs). This region contains the elastin gene (ELN, OMIM 130160), which is a functional candidate gene for IA. We have replicated this finding through linkage analyses in 13 extended pedigrees from...

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Identifiers

PMID: 14605871
DOI: 10.1007/s00439-003-1044-z

Genes

ELN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Confirmation of chromosome 7q11 locus for predisposition to intracranial aneurysm.PMID 14605871Read ↗

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