Article
Subarachnoid hemorrhage: tests of association with apolipoprotein E and elastin genes.
BMC medical genetics - 31 Jul 2007
Kaushal Ritesh, Woo Daniel, Pal Prodipto, Haverbusch Mary, Xi Huifeng, Moomaw Charles, Sekar Padmini, Kissela Brett, Kleindorfer Dawn, Flaherty Matthew, Sauerbeck Laura, Chakraborty Ranajit, Broderick Joseph, Deka Ranjan
Abstract excerpt
BACKGROUND: Apolipoprotein E (APOE) and elastin (ELN) are plausible candidate genes involved in the pathogenesis of stroke. We tested for association of variants in APOE and ELN with subarachnoid hemorrhage (SAH) in a population-based study. We genotyped 12 single nucleotide polymorphisms (SNPs) on APOE and 10 SNPs on ELN in a sample of 309 Caucasian individuals, of whom 107 are SAH cases and 202 are age-, race-,...
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