Article
Association of polymorphisms in the elastin gene with sporadic ruptured intracranial aneurysms and unruptured intracranial aneurysms in Chinese patients.
The International journal of neuroscience - 1 Jul 2013
Yang Shuaifeng, Wang Tinghua, You Chao, Liu Wenke, Zhao Ke, Sun Hong, Mao Boyong, Li Xuehua, Xiao Anqi, Mao XueYe, Zhang Heng
Abstract excerpt
It has been suggested that the elastin gene is a candidate gene for the development of intracranial aneurysms (IAs). We investigated the association of single-nucleotide polymorphisms (SNPs) in the elastin gene in sporadic subarachnoid hemorrhage and in patients with unruptured aneurysms in China. We genotyped 446 (47.9%) IA patients (308 ruptured and 138 unruptured) and 485 (52.1%) control subjects for seven...
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