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Article

A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.

Human molecular genetics - 15 May 2006

Akagawa Hiroyuki, Tajima Atsushi, Sakamoto Yoshiko, Krischek Boris, Yoneyama Taku, Kasuya Hidetoshi, Onda Hideaki, Hori Tomokatsu, Kubota Motoo, Machida Toshio, Saeki Naokatsu, Hata Akira, Hashiguchi Kazunari, Kimura Eizou, Kim Chul-Jin, Yang Tae-Ki, Lee Jong-Young, Kimm Kuchan, Inoue Ituro

Abstract excerpt

The rupture of an intracranial aneurysm (IA) results in subarachnoid hemorrhage, a catastrophic neurological condition with high morbidity and mortality. Following-up on our previous genome-wide linkage study in Japanese population, we extensively analyzed a 4.6 Mb linkage region around D7S2472 o...

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Identifiers

PMID: 16611674
DOI: 10.1093/hmg/ddl096

Genes

ELN
LIMK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16611674-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.PMID 16611674Read ↗

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