Article
Endothelial nitric oxide synthase rs1799983 gene polymorphism is associated with the risk of developing intracranial aneurysm.
Acta neurochirurgica - 1 May 2023
Usategui-Martín Ricardo, Jiménez-Arribas Paloma, Sakas-Gandullo Carmen, González-Sarmiento Rogelio, Rodríguez-Arias Carlos A
Abstract excerpt
PURPOSE: The intracranial aneurysm (IA) rupture is associated with a subarachnoid hemorrhage. One third of patients die, and one third remain depend for daily activities. Genetic factors are crucial in the formation and clinical evolution of IAs. Multiple loci have been associated with AIs, much of them implicating multiple pathways related to vascular endothelial maintenance and extracellular matrix integrity....
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