CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population.

doi:10.1210/jcem.80.1.7829637

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Article

CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population.

The Journal of clinical endocrinology and metabolism - 1 Jan 1995

Yanagawa T, Hidaka Y, Guimaraes V, Soliman M, DeGroot L J

Abstract excerpt

Graves' disease (GD) is an autoimmune thyroid disease. Multiple genetic factors are believed to be involved in its pathogenesis, but the factors are largely unknown, except for sex (female disease preponderance) and the role of human leukocyte antigen (HLA) genes on chromosome 6. To understand the mechanisms underlying the development of GD, a search for non-HLA-linked genes is crucial, and we tested several...

Topics

Abatacept
Alleles
Antigens, CD
Antigens, Differentiation
Base Sequence
CTLA-4 Antigen
Female
Gene Frequency
Genes
Genotype
Graves Disease
HLA Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunoconjugates

Male

Molecular Probes

Molecular Sequence Data

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 7829637
DOI: 10.1210/jcem.80.1.7829637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7829637-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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