Article
Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy.
Cancer research - 1 Apr 1993
Mok S C, Bell D A, Knapp R C, Fishbaugh P M, Welch W R, Muto M G, Berkowitz R S, Tsao S W
Abstract excerpt
The mutation of K-ras protooncogene was examined in 44 cases of borderline ovarian epithelial tumors and 18 cases of invasive ovarian carcinomas. In borderline tumors, K-ras mutations are a common feature, having been found in 21 of 44 cases (48%). Twenty of the 21 mutations were identified at co...
Topics
- Adenocarcinoma, Mucinous
- Base Sequence
- Codon
- Cystadenocarcinoma
- DNA Mutational Analysis
- Female
- Genes, ras
- Humans
- Molecular Sequence Data
- Mutation
- Ovarian Neoplasms