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Mutation Profiles of Ovarian Seromucinous Borderline Tumors in Japanese Patients.

Current oncology (Toronto, Ont.) - 18 May 2022

Sasamori Hiroki, Nakayama Kentaro, Razia Sultana, Yamashita Hitomi, Ishibashi Tomoka, Ishikawa Masako, Sato Seiya, Nakayama Satoru, Otsuki Yoshiro, Fujiwaki Ritsuto, Ishikawa Noriyoshi, Kyo Satoru

Abstract excerpt

Ovarian seromucinous tumors (SMBTs) are relatively rare, and their carcinogenesis is largely unknown. In this study, the molecular features of SMBTs in Japan are assessed. DNA was extracted from microdissected paraffin-embedded sections from 23 SMBT cases. Genetic mutations (KRAS, BRAF, PIK3CA, and ERBB2) were evaluated using Sanger sequencing. Immunohistochemistry for p53, ARID1A, and PTEN was also performed as...

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Identifiers

PMID: 35621684
DOI: 10.3390/curroncol29050294
PMCID: PMC9139622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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