Article
Molecular pathology of ovarian carcinomas.
Virchows Archiv : an international journal of pathology - 1 Aug 1998
Matias-Guiu X, Prat J
Abstract excerpt
There is evidence that ovarian cancer may be derived from the progressive transformation of benign and/or borderline tumours. Mutations involving different oncogenes and tumour suppressor genes accumulate during the process of malignant transformation, and the alterations of genes involved in the...
Topics
- BRCA2 Protein
- Cyclins
- Female
- Genes, BRCA1
- Genes, erbB-2
- Genes, p53
- Genes, ras
- Humans
- Microsatellite Repeats
- Mutation
- Neoplasm Proteins
- Ovarian Neoplasms
- Transcription Factors