k-ras mutation may be an early event in mucinous ovarian tumorigenesis.

doi:10.1097/00004347-200107000-00007

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

k-ras mutation may be an early event in mucinous ovarian tumorigenesis.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2001

Garrett A P, Lee K R, Colitti C R, Muto M G, Berkowitz R S, Mok S C

Abstract excerpt

We explored the possible pathogenetic pathway for mucinous ovarian tumorigenesis by examining the k-ras mutational patterns in ovarian mucinous tumors (OMTs) with benign, borderline, and invasive epithelium in which the different types of mucinous epithelium are in close proximity. Sixteen patients with ovarian mucinous borderline tumors (OMBTs) and 4 patients with grade 1 ovarian mucinous adenocarcinomas (OMCs)...

Read the complete abstract on PubMed

Topics

Adenocarcinoma, Mucinous
Adult
Aged
Aged, 80 and over
DNA Mutational Analysis
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genes, ras

Humans

Middle Aged

Mutation

Ovarian Neoplasms

Polymerase Chain Reaction

Polymorphism, Single-Stranded Conformational

Source

Open in PubMed

Identifiers

PMID: 11444200
DOI: 10.1097/00004347-200107000-00007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

k-ras mutation may be an early event in mucinous ovarian tumorigenesis.PMID 11444200Read ↗

Pre-invasive ovarian mucinous tumors are characterized by CDKN2A and RAS pathway aberrations.Semantic proximity Read ↗

Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy.Semantic proximity Read ↗

Pathogenetic pathways in ovarian endometrioid adenocarcinoma: a molecular study of 29 cases.Semantic proximity Read ↗

Origins and molecular pathology of ovarian cancer.Semantic proximity Read ↗

Molecular pathogenesis of ovarian borderline tumors: new insights and old challenges.Semantic proximity Read ↗

K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary.Semantic proximity Read ↗

Heterogeneous distribution of K-ras-mutated epithelia in mucinous ovarian tumors with special reference to histopathology.Semantic proximity Read ↗

Mucinous borderline ovarian tumors with BRAFV600E mutation may have low risk for progression to invasive carcinomas.Semantic proximity Read ↗

Mutations of BRAF and KRAS precede the development of ovarian serous borderline tumors.Semantic proximity Read ↗

Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms.Semantic proximity Read ↗

K-ras mutations in Müllerian inclusion cysts associated with serous borderline tumors of the ovary.Semantic proximity Read ↗

A multistep model for ovarian tumorigenesis: the value of mutation analysis in the KRAS and BRAF genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.