Article
[Cancer cells escape from failsafe programs in a simple Twist].
Bulletin du cancer - 1 Mar 2006
Puisieux Alain, Valsesia-Wittmann Sandrine
Abstract excerpt
A major obstacle to the expansion of abnormal cells with significant proliferative potential is the induction of either cellular senescence or programmed cell death. Consequently, oncogene-driven hyperproliferation must be associated with apoptosis inhibition to allow malignant outgrowth. The oncogenic cooperation of N-Myc and Twist 1 in the development of neuroblastoma, the most common and deadly solid tumour of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
