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Article

Regulation of Cancer Cell Survival, Migration, and Invasion by Twist: AKT2 Comes to Interplay

15 Feb 2008

Abstract excerpt

Metastasis, the foremost cause of mortality in cancer patients, is increasingly recognized as a coordinated biological process. The multistep process of metastasis posts difficulty in studying its mechanism and molecular basis. Recent works have shown that the basic helix-loop-helix transcriptional factor Twist and the serine/threonine kinase AKT play pivotal roles in tumor development and progression. Our recent...

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PMID: 18281467
DOI: 10.1158/0008-5472.can-07-5067

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Regulation of Cancer Cell Survival, Migration, and Invasion by Twist: AKT2 Comes to InterplayPMID 18281467Read ↗

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Twist Is Transcriptionally Induced by Activation of STAT3 and Mediates STAT3 Oncogenic FunctionSemantic proximity Read ↗

Snail2 is an Essential Mediator of Twist1-Induced Epithelial Mesenchymal Transition and MetastasisSemantic proximity Read ↗

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Involvement of the transcription factor twist in phenotype alteration through epithelial–mesenchymal transition in lung cancer cellsSemantic proximity Read ↗

<i>TWIST1</i> mediated transcriptional activation of <i>SPON2</i> drives colorectal peritoneal metastasis through activation of cancer-associated fibroblast signaling networkSemantic proximity Read ↗

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