Article
A Drosophila model to study the functions of TWIST orthologs in apoptosis and proliferation.
Cell death and differentiation - 1 Jun 2003
Gullaud M, Delanoue R, Silber J
Abstract excerpt
The twist gene has been characterized for its role in myogenesis in several species. In addition, in mammalian cultured cells, it has been shown that twist is a potential oncogene antagonizing p53-dependent apoptosis. To study, in vivo, the role of twist in apoptosis and proliferation, we constructed transgenic Drosophila lines allowing ectopic expression of different twist orthologs. We report that: (i)...
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