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Article

AKT-ions with a TWIST between EMT and MET.

Oncotarget - 20 Sept 2016

Tang Huifang, Massi Daniela, Hemmings Brian A, Mandalà Mario, Hu Zhengqiang, Wicki Andreas, Xue Gongda

Abstract excerpt

The transcription factor Twist is an important regulator of cranial suture during embryogenesis. Closure of the neural tube is achieved via Twist-triggered cellular transition from an epithelial to mesenchymal phenotype, a process known as epithelial-mesenchymal transition (EMT), characterized by a remarkable increase in cell motility. In the absence of Twist activity, EMT and associated phenotypic changes in...

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Share to Cell Movement
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Metastasis

Share to Proto-Oncogene Proteins c-akt

Share to Snail Family Transcription Factors

Share to Twist-Related Protein 1

Share to Zinc Finger E-box-Binding Homeobox 1

Source

Open in PubMed Open full text

Identifiers

PMID: 27623213
DOI: 10.18632/oncotarget.11232
PMCID: PMC5308764

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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