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Article

Amino acid residues 268-276 of the erythropoietin receptor contain an endocytosis motif and are required for erythropoietin-mediated proliferation.

FEBS letters - 8 May 2002

Flint-Ashtamker Galit, Eisen-Lev Ronit, Cohen Jacob, Jun-shen Huang Lily, Neumann Drorit

Abstract excerpt

Erythropoietin (EPO) promotes viability, proliferation and differentiation of mammalian erythroid progenitor cells via its specific cell surface receptor (EPO-R). We have previously shown that truncated EPO-Rs containing 267 amino acids or less were defective in internalization of (125)I-EPO, whereas internalization via a receptor derivative containing 276 amino acids was unaffected, thus directing focus to the...

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Source

Identifiers

PMID: 11997044
DOI: 10.1016/s0014-5793(02)02691-1

Genes

EPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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