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Article

Partial nucleotide sequence analysis of a French hepatitis C virus: implications for HCV genetic variability in the E2/NS1 protein.

The Journal of general virology - 1 Oct 1991

Kremsdorf D, Porchon C, Kim J P, Reyes G R, Bréchot C

Abstract excerpt

To contribute to the study of the genetic variability of hepatitis C virus (HCV) we have determined the nucleotide sequence of the E2/NS1 and NS3/NS4 regions of a French isolate using the polymerase chain reaction. Comparison of these nucleotide sequences with those available for American and Japanese isolates showed a significant genetic variability: 5 to 33% and 2 to 30% at the nucleic acid and amino acid...

Topics

Amino Acid Sequence
Base Sequence
DNA, Viral
Deoxyribonucleotides
Genetic Variation
Hepacivirus
Molecular Sequence Data
Polymerase Chain Reaction
Sequence Homology, Nucleic Acid
Viral Envelope Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1655961
DOI: 10.1099/0022-1317-72-10-2557

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1655961-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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