Article
Variability of the envelope regions of HCV in European isolates and its significance for diagnostic tools.
Archives of virology. Supplementum - 1 Jan 1993
Roggendorf M, Lu M, Fuchs K, Ernst G, Höhne M, Schreier E
Abstract excerpt
Following the original description of HCV in 1989 a tremendous amount of sequence data is now available. Based on the 8 complete nucleotide sequences published so far at least 4 genotypes can be distinguished. Partial sequences of additional HCV isolates indicate the existence of further genotypes. A serological typing is not yet possible. For detection of virus, reverse transcription and amplification of the 5'...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA, Viral
- Genetic Variation
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Molecular Sequence Data
- Phylogeny
- Sequence Homology, Amino Acid