Partial Nucleotide and Amino Acid Sequences of the Envelope and the Envelope/Nonstructural Protein-1 Gene Junction of Four Dengue-2 Virus Strains Isolated during the 1981 Cuban Epidemic

Abstract excerpt

In 1981, an epidemic of dengue hemorrhagic fever (DHF) caused by dengue-2 virus occurred in Cuba. This was the first DHF epidemic reported in the Western Hemisphere. In this study, we have analyzed four dengue-2 Cuban strains for two short genomic fragments: one on the envelope (E) glycoprotein and one at the E/nonstructural protein-1 (NS1) gene junction. The E segment of these 1981 Cuban isolates were more...

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