Evidence of two major genotypes of hepatitis C virus in France and close relatedness of the predominant one with the prototype virus.

doi:10.1016/0168-8278(91)90019-8

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Article

Evidence of two major genotypes of hepatitis C virus in France and close relatedness of the predominant one with the prototype virus.

Journal of hepatology - 1 Jan 1991

Li J S, Tong S P, Vitvitski L, Lepot D, Trépo C

Abstract excerpt

Hepatitis C virus (HCV) cDNA sequence in the nonstructural region NS3 was amplified from the serum of 66% French non-A, non-B hepatitis patients by the nested polymerase chain reaction. A 407 base-pair sequence was determined from four such cases, which revealed the presence of two different viru...

Topics

Antisense Elements (Genetics)
Base Sequence
Capsid
Cloning, Molecular
DNA, Viral
France
Genotype
Hepacivirus
Humans
Molecular Sequence Data
Oligonucleotide Probes
Polymerase Chain Reaction
Sequence Homology, Nucleic Acid
Viral Core Proteins
Viral Nonstructural Proteins

Source

Open in PubMed

Identifiers

PMID: 1668330
DOI: 10.1016/0168-8278(91)90019-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1668330-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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